Korean Circ J.  2021 Nov;51(11):881-898. 10.4070/kcj.2021.0227.

Pulsatile Hemodynamics and Coronary Artery Disease

  • 1Division of Cardiology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea
  • 2Department of Cardiology, Klinikum Wels-Grieskirchen GmbH, Wels, Austria


Coronary artery disease (CAD) is the leading cause of human death and has a high prevalence throughout the world. Therefore, it is important to detect CAD early and to apply individualized therapy according to the patients' risk. There is an increasing interest in pulsatile arterial hemodynamics in the cardiovascular area. Widely used measurements of arterial pulsatile hemodynamics include pulse pressure, pulse wave velocity and augmentation index. Here, we will review underlying pathophysiology linking the association of arterial pulsatile hemodynamics with CAD, and the usefulness of the measurements of pulsatile hemodynamics in the prediction of future cardiovascular events of CAD patients. Clinical and therapeutic implications will be also addressed.


Arterial stiffness; Pulse wave velocity; Wave reflections; Coronary artery disease; Pulsatile hemodynamics
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