Korean J Otorhinolaryngol-Head Neck Surg.
2021 Aug;64(8):576-579. 10.3342/kjorl-hns.2020.00402.
Oral Phase Dysphagia, the First Manifestation of Systemic Amyloidosis Associated with Multiple Myeloma
- Affiliations
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- 1Department of Otorhinolaryngology-Head and Neck Surgery, Inha University College of Medicine, Incheon, Korea
- 2Department of Pathology, Inha University College of Medicine, Incheon, Korea
- KMID: 2519756
- DOI: http://doi.org/10.3342/kjorl-hns.2020.00402
Abstract
- Amyloidosis is a disease in which abnormal proteins called amyloid accumulates in various tissues. In the head and neck area, the larynx is the most common site with the rare involvement of the tongue, causing symptoms of macroglossia. Most of amyloid light-chain (AL) amyloidosis are systemic amyloidosis accompanied with multiple myeloma (MM), where the involvement of tongue can be often observed. We report a case of AL amyloidosis with MM, initially with symptoms of dysarthria and dysphagia without macroglossia, but gradually over the years, macroglossia and high tongue stiffness were observed.
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Cited by 1 articles
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A Case of Glottic Amyloidosis Presenting as Leukoplakia
Seong Kyu Moon, Moon Seung Beag, Mi Ji Lee, Seung Woo Kim
Korean J Otorhinolaryngol-Head Neck Surg. 2022;65(5):293-295. doi: 10.3342/kjorl-hns.2022.00038.
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