J Korean Neurol Assoc.  2021 Aug;39(3):222-224. 10.17340/jkna.2021.3.21.

Lambert-Eaton Myasthenic Syndrome Presenting as Cerebellar Symptoms

Affiliations
  • 1Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
  • 2Department of Neurology, Inje University Sanggye Paik Hospital, Seoul, Korea

Abstract

A 79-year-old man visited neurology clinic due to gait ataxia and vertigo for 10 months. Neurologic examination revealed saccadic pursuit, mild dysmetria, impaired tandem gait, and areflexia that recovers after exercise. The amplitude of compound muscle action potentials recorded on the abductor digiti minimi increased up to 6,639.4% during repetitive nerve stimulation at 50 Hz stimulation. This case demonstrates that clinicians should consider Lambert-Eaton myasthenic syndrome as a differential diagnosis when a patient complains of gait ataxia and vertigo.

Keyword

Lambert-Eaton myasthenic syndrome; Cerebellar ataxia
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