Korean J Gastroenterol.  2021 Jul;78(1):59-64. 10.4166/kjg.2021.059.

Prostate Cancer Presenting with Pruritus and Cholestasis

Affiliations
  • 1Departments of Internal Medicine, Kangwon National University Hospital, Kangwon National University School of Medicine, Chuncheon, Korea
  • 2Departments of Anatomic Pathology, Kangwon National University Hospital, Kangwon National University School of Medicine, Chuncheon, Korea
  • 3Departments of Urology, Kangwon National University Hospital, Kangwon National University School of Medicine, Chuncheon, Korea

Abstract

Jaundice is a rare symptom of the paraneoplastic syndrome associated with prostate cancer. We report a case of metastatic prostate cancer that presented as jaundice. There was an absence of biliary obstruction and hepatic metastasis; therefore, the paraneoplastic syndrome was suggested as the etiology of cholestasis. Jaundice improved with the treatment of prostate cancer. In the literature, interleukin-6 has been suggested to be associated with paraneoplastic syndrome.

Keyword

Prostatic neoplasms; Cholestasis; Paraneoplastic syndromes; Interleukin-6
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