J Korean Soc Radiol.  2021 Jul;82(4):817-825. 10.3348/jksr.2021.0075.

Diagnosis of Hypersensitivity Pneumonitis: 2020 Clinical Practice Guideline

Affiliations
  • 1Department of Radiology, Korea University Anam Hospital, College of Medicine, Korea University, Seoul, Korea
  • 2Department of Radiology, Korea University Guro Hospital, College of Medicine, Korea University, Seoul, Korea
  • 3Department of Radiology, Korea University Ansan Hospital, College of Medicine, Korea University, Ansan, Korea

Abstract

Hypersensitivity pneumonitis (HP) is an interstitial lung disease (ILD) characterized by an inhaled inciting antigen that leads to the inflammation of the lung parenchyma and small airway with immunologic reactions. Over the last decades, the most effective therapeutic option for HP has been limited to antigen avoidance. The differential diagnosis of HP from other ILDs is the beginning of treatment as well as diagnosis. However, the presence of several overlapping clinical and radiologic features makes differentiating HP from other ILDs particularly challenging. In 2020, a multidisciplinary committee of experts from the American Thoracic Society, Japanese Respiratory Society, and Asociación Latinoamericana del Tórax suggested a new clinical practice guideline classifying HP into nonfibrotic and fibrotic phenotypes on the basis of chest high-resolution CT (HRCT) findings. Therefore, we introduced a new diagnostic algorithm based on chest HRCT in the clinical practice guideline for the diagnosis of HP.

Keyword

Hypersensitivity Pneumonitis; Interstitial Lung Disease; Diagnosis; Tomography; X-Ray Computed; Practice Guideline
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