Korean J Pain.  2021 Jun;34(3):332-338. 10.3344/kjp.2021.34.3.332.

Epidemiology of trigeminal neuralgia: an electronic population health data study in Korea

  • 1Department of Anesthesiology and Pain Medicine, Wonkwang University Hospital, Wonkwang University School of Medicine, Iksan, Korea
  • 2Department of Anatomy, Wonkwang University School of Medicine, Iksan, Korea
  • 3Jesaeng-Euise Clinical Anatomy Center, Wonkwang University School of Medicine, Iksan, Korea
  • 4Department of Nursing, Kunsan National University, Gunsan, Korea


Trigeminal neuralgia (TN) is one of the most painful disorder in the orofacial region, and many patients have suffered from this disease. For the effective management of TN, fundamental epidemiologic data related to the target population group are essential. Thus, this study was performed to clarify the epidemiological characteristics of TN in the Korean population. This is the first national study to investigate the prevalence of TN in Korean patients.
From 2014 to 2018, population-based medical data for 51,276,314 subscribers to the National Health Insurance Service of Korea were used for this study.
The incidence of TN was 100.21 per 100,000 person-years in the year of 2018 in Korea, and the male to female ratio was 1:2.14. The age group of 51-59 years had the highest prevalence of TN. Constant increases in medical cost, regional imbalance, and differences in prescription patterns by the medical specialties were showed in the management of TN.
The results in this study will not only help to study the characteristics of TN, but also serve as an important basis for the effective management of TN in Korea.


Big Data; Cohort Studies; Epidemiologic Studies; Facial Pain; Incidence; National Health Programs; Patient Acceptance of Health Care; Population Surveillance; Prevalence; Republic of Korea; Trigeminal Neuralgia
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