Korean J Dent Mater.  2021 Jun;48(2):89-98. 10.14815/kjdm.2021.48.2.89.

Physical and biodegradable properties of 3D printed resorbable membranes for periodontal guided tissue regenerations

Affiliations
  • 1Department and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of Dentistry, Seoul, Republic of Korea
  • 2BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Republic of Korea
  • 3Korea Conformity Laboratories, Incheon, Republic of Korea
  • 4Department of Dental Biomaterials Science, School of Dentistry, Seoul National University, Seoul, Korea

Abstract

The purpose of this study was to compare physical and biodegradable properties of 3D printed resorbable membranes that are used for guided tissue regenerations in periodontal tissues. Three types of 3D printed membranes (two types of non β-TCP and one type of β-TCP) were considered. The form and element compositions of 3D printed membranes were analyzed by field-emission scanning electron microscopy (FE-SEM) with energy-dispersive X-ray spectroscopy (EDS). Porosity and pore size were measured using Micro-CT. Also, tensile strength, biodegradability tests were performed. Statistical analyses were carried in tensile strength and cell viability test (p<0.05). The result of SEM images with EDS analyses showed linear layers of lattice structure with presence of C and O in all groups. There was a slight difference in Ca and P among some groups. Tensile strength was significantly different among all groups (p<0.05), and biodegradability showed that the group containing β-TCP resulted in the fastest degradation rate. Therefore, the results of this study concluded that the 3D printed resorbable membrane has variable physical and biodegradable properties for clinical use, where such information would be useful to be considered for the future development of related products and clinical application of the products.

Keyword

3D Printing; Membrane; Guided tissue regeneration; Tensile strength; Degradation
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