J Korean Med Sci.  2021 Jun;36(25):e181. 10.3346/jkms.2021.36.e181.

The First Case of Multisystem Inflammatory Syndrome in Adult after COVID-19 in Korea

Affiliations
  • 1Department of Infectious Disease, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

Abstract

Multisystem inflammatory disease in children is a Kawasaki disease like illness occurring after severe acute respiratory syndrome coronavirus 2 infection in children. As the pandemic progresses, similar syndromes were also reported in adult with a decreased incidence. Multisystem inflammatory syndrome in adults (MIS-A) can be characterized with shock, heart failure, and gastrointestinal symptoms with elevated inflammatory markers after coronavirus disease 2019 (COVID-19) infection. Herein, we describe the first case of MIS-A in South Korea. A 38-year-old man presented to our hospital with a 5-day history of abdominal pain and fever. He had been treated with antibiotics for 5 days at the previous hospital, but symptoms had worsened and he had developed orthopnea on the day of presentation. He suffered COVID-19 six weeks ago. Laboratory data revealed elevated white blood cell counts with neutrophil dominance, C-reactive protein, and B-type natriuretic peptide. Chest X-ray showed normal lung parenchyme and echocardiography showed severe biventricular failure with normal chamber size. We diagnosed him as MIS-A and treated with intravenous immunoglobulin and steroid.

Keyword

COVID-19; Multisystem Inflammatory Syndrome; Adult

Figure

  • Fig. 1 Clinical course and treatment of the patient with multisystem inflammatory syndrome in adults.COVID-19 = coronavirus disease 2019, IVIG = intravenous immunoglobulin, BNP = B-type natriuretic peptide.


Cited by  2 articles

Multisystem Inflammatory Syndrome in an Adult Following COVID-19 mRNA Vaccination: Successful Treatment With Medium-Dose Steroids and Colchicine
Hyo-Jin Lee, Yeon Jeong Jeong, Youn Jeong Kim, Si-Hyun Kim
J Korean Med Sci. 2022;37(41):e299.    doi: 10.3346/jkms.2022.37.e299.

Comparison of COVID-19-associated multisystem inflammatory syndrome in children (MIS-C) and Kawasaki disease shock syndrome: case reports and literature review
Songmi Lee, Danbi Kim, Beom Joon Kim, Jung Woo Rhim, Soo-Young Lee, Dae Chul Jeong
J Rheum Dis. 2023;30(4):272-277.    doi: 10.4078/jrd.2023.0022.


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