Res Vestib Sci.  2021 Jun;20(2):37-44. 10.21790/rvs.2021.20.2.37.

Update on Genetic Study of Vestibular Disorder

  • 1Department of Neurology, Pusan National University School of Medicine, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea


The wide availability of next-generation sequencing has enabled a rapid progress in the discovery of genetic variants associated with many disorders. However, the contribution of genetic factors in vestibular disorders is largely unknown due to the low prevalence of familial disorders and the clinical diversity. A detailed clinical characterization of patients and a choice of proper genetic tests are required to identify the genetic contribution in vestibular disorders. In this review, we will introduce a genetic approach for vestibular disorders and update the evidences to support the genetic contribution in vestibular disorders.


Genetic studies; Vestibular disorder; Next generation sequencing; Gene expression profiling; 유전학 연구; 전정질환; 차세대 염기서열분석; 유전자 발현 분석
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