Korean J Otorhinolaryngol-Head Neck Surg.  2021 Apr;64(4):258-262. 10.3342/kjorl-hns.2020.00143.

Human Papilloma Virus-Related Metachronous Tracheal Cancer in a Patient with Tonsillar Cancer

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea

Abstract

Second primary malignancy (SPM) is a well-known cause of death in head and neck cancers. Recently, with reports of many incidences of human papilloma virus (HPV) associated SPM, the disease has been widely investigated. We report a HPV-positive tracheal cancer in a 49-yearold male who had been diagnosed with HPV-positive squamous cell carcinoma of the right tonsil within intervals of two years. In this case, the metachronous tracheal cancer lesion as well as the primary tonsillar cancer showed the same subtype HPV-16.

Keyword

Human papilloma virus; Metachronous cancer; Tonsillar cancer; Tracheal cancer
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