J Korean Neurol Assoc.  2021 May;39(2 Suppl):15-23. 10.17340/jkna.2021.2.17.

Clinical Scales for the Evaluation of Myopathy Patients

Affiliations
  • 1Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea

Abstract

With the rapid increase in the number of clinical trials in myopathy over the past decade, there is an increasing need for clinical scales to reflect patient’s clinical status. This article outlines the process of identifying possible measures. Detailed consideration has been given to key measures of muscle strength, function, and disability. As well as the usual assessment of the validity and reliability of the measures, three key characteristics were identified as necessary to the assessment of clinical scales used in health care: 1) the type of scale; 2) the clinical significance of the property being measured; and 3) the mathematical properties of the data. Consideration of such aspects facilitates the choice of clinical scales and the interpretation of data.

Keyword

Muscular diseases; Motor activity; Treatment outcome; Clinical trial
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