Nucl Med Mol Imaging.  2021 Apr;55(2):100-102. 10.1007/s13139-021-00682-x.

False-Positive Gallium-68 DOTATATE PET/CT in Vertebral Hemangioma

  • 1Department of Medical Imaging, Ministry of National Guard - Health Affaires, Riyadh, Saudi Arabia
  • 2King Abdullah International Medical Research Center, Riyadh, Saudi Arabia
  • 3King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia
  • 4Department of Radiology and Medical Imaging, College of Medicine, Qassim University, Qassim, Saudi Arabia


A healthy 52-year-old man started to have few minutes spells of palpitation, tachycardia, hot flashes, and chest tightness. He had a lab work-up for carcinoid, including 5-hydroxyindoleacetic acid (5-HIAA), which was negative. Months later, his symptoms became worse which warranted further investigation to exclude carcinoid disease. Gallium-68 DOTATATE positron emission tomography combined with computed tomography (PET/CT) scanning was performed to assess the patient for carcinoid tumor. It showed foci of radiotracer avidity in the thoracic and lumber spine. Magnetic resonance imaging (MRI) for the vertebral lesions showed atypical hemangioma. Subsequently, follow-up serum chromogranin A testing was negative.


Somatostatin receptors; Vertebral hemangioma; 68-Gallium DOTATATE; Magnetic resonance imaging
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