Radiat Oncol J.
2021 Mar;39(1):72-77. 10.3857/roj.2020.00591.
Clinical behaviour and outcome in pediatric glioblastoma: current scenario
- Affiliations
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- 1Department of Radiotherapy and Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
- 2Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
- 3Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India
- 4Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, India
- KMID: 2514516
- DOI: http://doi.org/10.3857/roj.2020.00591
Abstract
- Pediatric glioblastoma (pGBM) is a rare entity accounting for only approximately 3% of all childhood brain tumors. Treatment guidelines for pGBM have been extrapolated from those in adult glioblastoma. Rarity of pGBM and underrepresentation of pediatric population in major studies precludes from defining the ideal treatment protocol for these patients. Maximum safe resection is performed in most of the cases followed by postoperative radiotherapy in children over 3 years of age. Benefit of temozolomide is unclear in these patients. Here, we present the clinicopathological details and outcome of six pGBM patients treated at our institute in 2018–2019.
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