Yeungnam Univ J Med.  2021 Jan;38(1):70-73. 10.12701/yujm.2020.00304.

Co-existence of relapsing polychondritis and Crohn disease treated successfully with infliximab

Affiliations
  • 1Division of Gastroenterology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea
  • 2Division of Rheumatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea

Abstract

Relapsing polychondritis (RP) is a rare, progressive immune-mediated systemic inflammatory disease of unknown etiology, characterized by recurrent inflammation of cartilaginous structures. Approximately 30% of RP cases are associated with other autoimmune diseases. However, the co-occurrence of RP and Crohn disease (CD) has rarely been reported. Herein, we present a 35-year-old woman diagnosed with RP and CD, who was refractory to initial conventional medications, including azathioprine and glucocorticoid, but who subsequently responded to infliximab (IFX). For both diseases, remission was sustained with IFX. There has been no previous report regarding the successful treatment of co-existing RP and CD with IFX.

Keyword

Crohn disease; Inflammatory bowel diseases; Infliximab; Polychondritis, relapsing
Full Text Links
  • YUJM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr