Biomol Ther.  2021 Jan;29(1):1-10. 10.4062/biomolther.2020.178.

COVID-19 Vaccine: Critical Questions with Complicated Answers

Affiliations
  • 1Department of Soil, Water and Environment, University of Dhaka, Dhaka 1000, Bangladesh
  • 2School of Health & Society, University of Wollongong, NSW 2500, Australia
  • 3Department of Biomedical Engineering, Khulna University of Engineering and Technology, Khulna 9203, Bangladesh
  • 4Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh
  • 5Department of Medicine, School of Clinical Sciences, Monash University, Victoria 3800, Australia
  • 6Biological Resources Utilization Department, National Institute of Biological Resources, Incheon 22689, Republic of Korea
  • 7Department of Integrative Biotechnology, and Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon 16419, Republic of Korea

Abstract

COVID-19 has caused extensive human casualties with significant economic impacts around the globe, and has imposed new challenges on health systems worldwide. Over the past decade, SARS, Ebola, and Zika also led to significant concerns among the scientific community. Interestingly, the SARS and Zika epidemics ended before vaccine development; however, the scholarly community and the pharmaceutical companies responded very quickly at that time. Similarly, when the genetic sequence of SARSCoV-2 was revealed, global vaccine companies and scientists have stepped forward to develop a vaccine, triggering a race toward vaccine development that the whole world is relying on. Similarly, an effective and safe vaccine could play a pivotal role in eradicating COVID-19. However, few important questions regarding SARS-CoV-2 vaccine development are explored in this review.

Keyword

COVID-19; Vaccine; Vaccine backfires; Vaccine safety
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