Infect Chemother.  2020 Dec;52(4):634-640. 10.3947/ic.2020.52.4.634.

Coxsackievirus A6-induced HandFoot-and-Mouth Disease Mimicking Stevens-Johnson Syndrome in an Immunocompetent Adult

Affiliations
  • 1Division of Infectious Disease, Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea
  • 2Department of Dermatology, Inje University Haeundae Paik Hospital, Busan, Korea
  • 3Department of Otorhinolaryngology, Head and Neck Surgery, Inje University Haeundae Paik Hospital, Busan, Korea
  • 4Department of Pathology, Inje University Haeundae Paik Hospital, Busan, Korea
  • 5Division of Allergology, Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea
  • 6Division of Infectious Disease, Department of Internal Medicine, Chungnam National University Sejong Hospital, Sejong, Korea

Abstract

Hand-foot-and-mouth disease, a highly contagious viral infection, occurs more common in children than in adults. However, there was a recent outbreak of Coxsackievirus A6-induced infection with an atypical presentation among the adult population. Stevens– Johnson syndrome is a severe mucocutaneous disease characterized by extensive necrosis and detachment of the epidermis, and this condition is commonly caused by medications. Herein, we describe a 30-year-old male patient taking allopurinol for the management of gout. The patient presented with numerous erythematous papules, vesicles, and patches with mucosal eruptions on the whole body, oral mucositis, and fever, and he was finally diagnosed with hand-foot-and-mouth disease.

Keyword

Adult; Coxsackievirus A6; Hand-foot-and-mouth disease; Stevens–Johnson syndrome; Allopurinol
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