Korean J Fam Pract.  2020 Dec;10(6):469-473. 10.21215/kjfp.2020.10.6.469.

Association between Sitting Time and Hyperuricemia in Korean Adults: Results from the 2016– 2018 Korea National Health and Nutrition Examination Survey

Affiliations
  • 1Department of Family Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea
  • 2Department of Family Medicine, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea

Abstract

Background
Recent studies have indicated that hyperuricemia is associated with metabolic syndrome and cardiovascular diseases. We aimed to examine the association between sitting time and hyperuricemia in Korean adults.
Methods
This study included 16,535 adults aged ≥19 years who participated in the 2016–2018 Korea National Health and Nutrition Examination Survey. Hyperuricemia was defined as a serum uric acid level of ≥7.0 mg/dL in men and ≥6.0 mg/dL in women. The odds ratios and 95% confidence intervals of hyperuricemia according to sitting time were calculated using a multivariable logistic regression analysis.
Results
The mean serum uric acid levels were significantly higher in participants with sitting times of ≥5 hours/day than those with sitting times of <5 hours/day in total participants, males, and females. The proportion of hyperuricemia was also significantly higher in participants with sitting times of ≥5 hours/day than those with sitting times of <5 hours/day in the total participants and males. Before and after adjusting for confounding variables, sitting times of ≥5 hours/day were associated with increased odds of hyperuricemia as compared with sitting times of <5 hours/day in total participants.
Conclusion
Our findings suggest that longer sitting time is associated with risk of hyperuricemia, and sitting time is an independent factor for hyperuricemia in Korean adults.

Keyword

Uric Acid; Hyperuricemia; Sitting Time; Korea National Health and Nutrition Examination Survey
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