Korean J Transplant.  2020 Dec;34(Supple 1):S163. 10.4285/ATW2020.PO-1132.

Living donor liver transplantation at the Pusan National University Yangsan Hospital, Korea: result of living donor hepatectomy in a single center

• Ko HJ
• Ryu JH
• Yang K
• Choi BH
• Lee TB
• Sim JR

• KMID: 2509353
• DOI: http://doi.org/10.4285/ATW2020.PO-1132

Abstract

Background
Living donor liver transplantation is currently the most feasible treatment method for patients with end-stage liver disease. We discuss the results of living donor hepatectomy in our single center for 10 years, including donor characteristics and postoperative outcomes, and directions for improvement.
Methods
The 261 living donors underwent liver donation surgery were reviewed retrospectively from May 2010 to May 2020 at Pusan National University Yangsan Hospital.
Results
The ages of donors ranged from 16 to 64 years old, and 182 male and 79 female. Liver grafts were five types, 110 (44.9%) in caudal middle hepatic vein trunk preserved right lobe, 105 (42.5%) in modified right lobe, 16 (6.5%) in extended right lobe, 14 (5.7%) in left lobe, and one (0.4%) in right posterior segment. The average weight of the graft was 686.2 g, the volume was 37.5%, and the average of body mass index of the donor was 23.4 kg/㎡. Of 261 donors, there was no mortality and no postoperative hepatic failure or multi-organ failure. The average operation time was 372.7 minutes, the mean length of hospital stay was 13.7 days, the intensive care unit (ICU) stay was 1.02 days, and the intraoperative transfusion rate was 1.5%. Postoperative complications occurred in 44 donors. According to Clavien-Dindo classification, grade I complications occurred in 29 patients (11.1%), grade II in one patient (0.4%), grade III in 15 patients (5.7%) and there was no case of grade IV and V. Grade III or more severe complications requiring invasive procedure or surgical treatment were seven cases of biliary stenosis or leakage, five portal stenosis, one duodenal ulcer bleeding, one ascites, and one bleeding.
Conclusions
Although limitations of retrospective data and short follow-up period, postoperative outcome of liver donor was relatively good. Further study with long-term follow-up and minimally invasive and refined surgical techniques to reduce minor complications are needed.