Investig Magn Reson Imaging.  2020 Jun;24(2):85-89. 10.13104/imri.2020.24.2.85.

CT and MRI Findings of Small Bowel Involvement of Amyloidosis Mimicking Small Bowel Polyposis Syndrome: a Case Report

  • 1Department of Radiology, Wonkwang University School of Medicine & Hospital, Iksan, Korea
  • 2Department of Pathology, Wonkwang University School of Medicine & Hospital, Iksan, Korea


Amyloidosis is an all-inclusive disease of deposition of amyloid proteins in the extracellular spaces, which in localized or systemic form cause tissue damage and dysfunction. Herein, we report a case of small bowel involvement of systemic amyloidosis presenting with multiple polypoid wall thickening mimicking small bowel polyposis syndrome in an age 75 male. Interestingly, polypoid wall thickening and amyloidoma showed hypointensity on T2-weighted images. To our knowledge, there has been no literature describing MRI findings of poylpoid wall thickening and amyloidoma. Although the underlying mechanisms are unclear and need validation, hypointensity on T2-weighted images could be valuable in diagnosing small bowel involvement of amyloidosis in patients presenting with poylpoid wall thickening and amyloidoma.


Small bowel; Intestinal; Amyloidosis; Amyloidoma; Computed tomography; Magnetic resonance imaging
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