Nucl Med Mol Imaging.  2020 Feb;54(1):63-64. 10.1007/s13139-019-00628-4.

Clinical Applications of 68Ga-PSMA PET/CT on Residual Disease Assessment of Juvenile Nasopharyngeal Angiofibroma (JNA)

Affiliations
  • 1Department of Otorhinolaryngology & Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India
  • 2Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India

Abstract

We present a case of a 16-year-old boy who underwent 68Ga-PSMA PET/CT for residual disease assessment of juvenile nasal angiofibroma. Positive uptake was noted in residual tumor on PET/CT imaging. However, there was no abnormal uptake in surrounding scar tissues as compared with contrast-enhanced magnetic resonance imaging. These findings were confirmed by biopsy from the scar tissue on posterior ethmoids. 68Ga-PSMA PET/CT may be a potentially valuable tool especially in distinguishing recurrences from surgical site reparative tissue and in planning and delivering stereotactic radiotherapy.

Keyword

Angiofibroma; PSMA PET-CT; Juvenile nasopharyngeal angiofibroma; MRI
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