J Clin Neurol.
2020 Oct;16(4):547-555. 10.3988/jcn.2020.16.4.547.
Antiepileptic Drug Selection According to Seizure Type in Adult Patients with Epilepsy
- Kim H
1 - Kim DW2
- Lee ST3
- Byun JI4
- Seo JG5
- No YJ6
- Kang KW7
- Kim D8
- Kim KT9
- Cho YW9
- Yang KI10
- on behalf of the Drug Committee of Korean Epilepsy Society
- Affiliations
-
- 1Department of Neurology, Catholic Kwandong University College of Medicine, International St. Mary’s Hospital, Incheon, Korea
- 2Department of Neurology, Konkuk University School of Medicine, Seoul, Korea
- 3Department of Neurology, Seoul National University Hospital, Seoul, Korea
- 4Department of Neurology, Kyunghee University Hospital at Gangdong, Seoul, Korea
- 5Department of Neurology, School of Medicine, Kyungpook National University, Daegu, Korea
- 6Department of Neurology, Samsung Noble County, Yongin, Korea
- 7Department of Neurology, Chonnam National University Hospital, Chonnam National University School of Medicine, Gwangju, Korea
- 8Department of Neurology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea
- 9Department of Neurology, Keimyung University, School of Medicine, Daegu, Korea
- 10Department of Neurology, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan, Korea
- KMID: 2506777
- DOI: http://doi.org/10.3988/jcn.2020.16.4.547
Abstract
- Epilepsy is a common neurological disorder that is mainly treated using antiepileptic drugs. Several antiepileptic drugs such as phenobarbital, phenytoin, primidone, and ethosuximide were developed in the early 20th century. More than 10 types of antiepileptic drugs have been developed since the 1990s, and there are now more than 20 antiepileptic drugs in active clinical use. The choice of antiepileptic drugs is based on the clinical features of the seizure types, electroencephalogram findings, epileptic syndrome, and drug stability. Currently there are 19 antiepileptic drugs approved by the Korean Food and Drug Administration, 18 of which (with the exclusion of brivaracetam) are covered by the National Health Insurance Service in Korea. We reviewed the selection of antiepileptic drugs according to the classification of epileptic seizures.
