Arch Plast Surg.  2020 Sep;47(5):444-450. 10.5999/aps.2020.00381.

Effects of hyperbaric oxygen on graft survival outcomes in composite grafting for amputated fingertip injury

  • 1Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea
  • 2Department of Plastic and Reconstructive Surgery, Yonsei University Wonju College of Medicine, Wonju, Korea
  • 3Department of Biostatistics, Yonsei University Wonju College of Medicine, Wonju, Korea


Fingertip injuries are the most common type of traumatic injury treated at emergency departments and require prompt and adequate interventions for favorable wound survival outcomes. Hyperbaric oxygen (HBO2) therapy is well known for its many positive effects on wound healing. We hypothesized that treatment with HBO2 would improve the graft survival outcomes of amputated fingertip injuries treated with composite grafts.
This retrospective observational study included fingertip amputations that were treated between January 2013 and December 2017. A conventional group and an HBO2 therapy group were statistically compared to evaluate the effect of HBO2 treatment. Graft survival was categorized as either success or failure.
Among 55 cases (digits), 34 digits were conventionally treated, while 21 digits were treated with HBO2. No statistically significant differences were observed between the groups with regard to general characteristics. Among patients with guillotine-type injuries, the composite graft success rate was statistically significantly higher in the group that received HBO2 therapy than in the conventional group (P=0.0337). Overall, the HBO2 group also demonstrated a statistically significantly shorter healing time than the conventional group (P=0.0075). As such, HBO2 treatment facilitates composite graft survival in cases of fingertip injury.
HBO2 treatment was associated with an increased composite graft survival rate in guillotine-type fingertip injuries and reduced the time required for grafts to heal.


Composite tissue allografts; Amputation; Hyperbaric oxygen therapy
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