J Korean Assoc Oral Maxillofac Surg.  2020 Aug;46(4):275-281. 10.5125/jkaoms.2020.46.4.275.

Leiomyosarcoma of the jaw: case series

Affiliations
  • 1Department of Oral and Maxillofacial Surgery, Seoul National University Dental Hospital, Seoul, Korea
  • 2Clinical Translational Research Center for Dental Science, Seoul National University Dental Hospital, Seoul, Korea
  • 3Oral Cancer Center, Seoul National University Dental Hospital, Seoul, Korea
  • 4Department of Oral and Maxillofacial Surgery, Inje University Busan Paik Hospital, Busan, Korea
  • 5Department of Oral Pathology, Seoul National University Dental Hospital, Seoul, Korea
  • 6Dental Research Institute, Seoul National University, Seoul, Korea

Abstract


Objectives
Leiomyosarcoma is a malignant neoplasm that affects smooth muscle tissue and it is very rare in the field of oral and maxillofcial surgery. The purpose of this study was to obtain information on diagnosis of and treatment methods for leiomyosarcoma by retrospectively reviewing of the cases.
Patients and Methods
The study included nine patients who were diagnosed with leiomyosarcoma in the Department of Oral and Maxillofacial Surgery at Seoul National University Dental Hospital. The subjects were analyzed with respect to sex, age, clinical features, primary site of disease, treatment method, recurrence, and metastasis.
Results
Particular clinical features included pain, edema, mouth-opening limitations, dysesthesia, and enlarged lymph nodes. All cases except one were surgically treated, and recurrence was found in two cases. Four of nine patients were followed up without recurrence and one patient underwent additional surgery due to recurrence.
Conclusion
In our case series, notable symptoms included pain, edema, mouth-opening limitations, and dysesthesia; however, it was difficult to label these as specific symptoms of leiomyosarcoma. Considering the aggressive characteristics of the disease and poor prognosis, surgical treatment is necessary with careful consideration of postoperative radiotherapy and chemotherapy.

Keyword

Leiomyosarcoma; Mouth neoplasm; Case series
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