Korean Circ J.  2020 Aug;50(8):645-657. 10.4070/kcj.2020.0098.

Ethnic Differences in Oral Antithrombotic Therapy

  • 1Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, Seoul, Korea


Oral antithrombotic therapy (antiplatelet therapy and anticoagulation therapy) is a key element of pharmacotherapy in patients with cardiovascular (CV) disease. Several reports of ethnic differences have suggested that there may be difference therapeutic requirements and response to therapy for antithrombotic therapy. In particular for East Asians, there seems to be a lower incidence of ischemic outcomes and a higher incidence of bleeding outcomes compared to Westerners. The purpose of this review is to describe the ethnicity-related differences in antithrombotic therapy for CV disease and to discuss the need to establish a more effective and targeted antithrombotic treatment strategy in East Asians.


Ethnic difference; Oral anthrombotic therapy; Antiplatelet therapy; Anticoagulation
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