Korean J Pain.  2020 Jul;33(3):234-244. 10.3344/kjp.2020.33.3.234.

Patients’ perception about opioids and addiction in South Korea

Affiliations
  • 1Department of Anesthesiology and Pain Medicine, Konkuk University School of Medicine, Seoul, Korea
  • 2Department of Anesthesiology and Pain Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea
  • 3Department of Anesthesiology and Pain Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea
  • 4Department of Anesthesiology and Pain Medicine, Jeong-clinic, Seoul, Korea
  • 5Department of Anesthesiology and Pain Medicine, The Catholic University of Korea, Eunpyeong St. Mary’s Hospital, Seoul, Korea
  • 6Department of Anesthesiology and Pain Medicine, Inje University Seoul Paik Hospital, Seoul, Korea
  • 7Department of Anesthesiology and Pain Medicine, Jeju National University School of Medicine, Jeju, Korea
  • 8Department of Anesthesiology and Pain Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul, Korea

Abstract

Background
Chronic pain affects approximately 22% of the world’s population. Opioids can be useful in chronic pain management. However, some patients have negative perception of opioids. The purpose of this research was to evaluate patients’ perception about opioids and investigate problems associated with prescribing and taking opioids in South Korea.
Methods
Patients who visited a pain clinic in 14 university hospitals of South Korea from September through October 2018 were asked to complete anonymous questionnaires about taking opioids.
Results
Of the 368 patients that were surveyed (female 53.3%, male 46.7%), 56.8% were prescribed opioids. In the opioid group, 92.8% patients had heard of opioids from their doctor and 72.6% of them had a positive perception about opioids. The side effects associated with opioid use were constipation (35.4%), dizziness (24.6%), nausea and vomiting (17.4%), dysuria (6.2%), and addiction (2.0%). In the no opioid group, the primary sources of information about opioids were doctors (49.2%), mass media (30.8%), and the internet (16.2%). The main reasons why 39.0% patients did not take opioids were fear of addiction (57.7%) and side effects (38.5%). There were 71.5% and 60.9% patients in the opioid and no opioid group, respectively, who wished to take opioids when their numeric rating scale pain score was ≥ 7.
Conclusions
Perception of opioids among patients who take them was either neutral or positive. However, 39.0% patients who have not been prescribed opioids did not want an opioid prescription, citing fear of addiction and side effects as the primary reasons.

Keyword

Analgesics, Opioid; Behavior, Addictive; Chronic Pain; Drug-Related Side Effects and Adverse Reactions; Opioid-Related Disorders; Outpatients; Pain Management; Physicians; Surveys and Questionnaires

Figure

  • Fig. 1 Have you ever been prescribed opioids? (asked in both the opioid groups).

  • Fig. 2 What are the most severe side effects that you have experienced? (asked in the opioid group).

  • Fig. 3 (A) Did your doctor ask you regarding opioids and explain their side effects? (asked in the opioid group). (B) What is your perception regarding opioid medication? (asked in the opioid group).

  • Fig. 4 (A) In Korea, public health insurance provides coverage for the prescription of opioids up to 30 days for the non-cancer pain treatment. What is your opinion regarding this limit? (asked in the opioid group). (B) If you think this limit should be increased, then please tell us why? (C) If you think this limit should be decreased, then please tell us why?

  • Fig. 5 (A) In Korea, public health insurance provides coverage for opioid prescription for pain treatment. Insurance covered opioid dosage is non-restricted for the cancer pain treatment, but it is limited for the non-cancer pain treatment. What is your opinion regarding this limit on opioid dosage? (asked in the opioid group). (B) If you think insurable prescription dosages should be increased, then please tell us why? (C) If you think insurable prescription dosages should be decreased, then please tell us why?

  • Fig. 6 (A) If your physician informs you regarding the requirement to prescribe opioids for pain control, would you consume them? (asked in the no opioid group). (B) If you deny, then please tell us why?

  • Fig. 7 What is your source of opioid information? (asked in the no opioid group).

  • Fig. 8 Did you know that differences between medically prescribed opioids and illegally distributed drugs exist? (asked in both the opioid groups).

  • Fig. 9 What is the pain score at which you would start taking opioids if they are prescribed? (asked in both the opioid groups).


Cited by  1 articles

Actual situation and prescribing patterns of opioids by pain physicians in South Korea
Min Jung Kim, Ji Yeon Kim, Yun Hee Lim, Sung Jun Hong, Jae Hun Jeong, Hey Ran Choi, Sun Kyung Park, Jung Eun Kim, Min Ki Lee, Jae Hun Kim
Korean J Pain. 2022;35(4):475-487.    doi: 10.3344/kjp.2022.35.4.475.


Reference

1. Gureje O, Von Korff M, Simon GE, Gater R. 1998; Persistent pain and well-being: a World Health Organization Study in primary care. JAMA. 280:147–51. DOI: 10.1001/jama.280.2.147. PMID: 9669787.
2. Ahacic K, Kåreholt I. 2010; Prevalence of musculoskeletal pain in the general Swedish population from 1968 to 2002: age, period, and cohort patterns. Pain. 151:206–14. DOI: 10.1016/j.pain.2010.07.011. PMID: 20708842.
Article
3. Toth C, Lander J, Wiebe S. 2009; The prevalence and impact of chronic pain with neuropathic pain symptoms in the general population. Pain Med. 10:918–29. DOI: 10.1111/j.1526-4637.2009.00655.x. PMID: 19594844.
Article
4. Breivik H, Collett B, Ventafridda V, Cohen R, Gallacher D. 2006; Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. Eur J Pain. 10:287–333. DOI: 10.1016/j.ejpain.2005.06.009. PMID: 16095934.
Article
5. Fine PG. 2011; Long-term consequences of chronic pain: mounting evidence for pain as a neurological disease and parallels with other chronic disease states. Pain Med. 12:996–1004. DOI: 10.1111/j.1526-4637.2011.01187.x. PMID: 21752179.
Article
6. Dworkin RH, O’Connor AB, Audette J, Baron R, Gourlay GK, Haanpää ML, et al. 2010; Recommendations for the pharmacological management of neuropathic pain: an overview and literature update. Mayo Clin Proc. 85(3 Suppl):S3–14. DOI: 10.4065/mcp.2009.0649. PMID: 20194146. PMCID: PMC2844007.
Article
7. Attal N, Cruccu G, Baron R, Haanpää M, Hansson P, Jensen TS, et al. 2010; EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision. Eur J Neurol. 17:1113–e88. DOI: 10.1111/j.1468-1331.2010.02999.x. PMID: 20402746.
Article
8. Kim YD. 2019; Opioid: toward an effective strategy for better use. Korean J Pain. 32:67–8. DOI: 10.3344/kjp.2019.32.2.67. PMID: 31091504. PMCID: PMC6549590.
Article
9. Moore RA, McQuay HJ. 2005; Prevalence of opioid adverse events in chronic non-malignant pain: systematic review of randomised trials of oral opioids. Arthritis Res Ther. 7:R1046–51. DOI: 10.1186/ar1782. PMID: 16207320. PMCID: PMC1257433.
10. Sun VC, Borneman T, Ferrell B, Piper B, Koczywas M, Choi K. 2007; Overcoming barriers to cancer pain management: an institutional change model. J Pain Symptom Manage. 34:359–69. DOI: 10.1016/j.jpainsymman.2006.12.011. PMID: 17616336. PMCID: PMC2747495.
Article
11. Maltoni M. 2008; Opioids, pain, and fear. Ann Oncol. 19:5–7. DOI: 10.1093/annonc/mdm555. PMID: 18073220.
Article
12. Baik JS. 2017; Guidelines for prescribing opioids for chronic non-cancer pain in Korea: can you overcome “opiophobia”? Korean J Pain. 30:1–2. DOI: 10.3344/kjp.2017.30.1.1. PMID: 28119766. PMCID: PMC5256267.
Article
13. Han T. 2001; Opioids in cancer and non-cancer pain management in Korea: the past, present and future. Eur J Pain. 5 Suppl A:73–8. DOI: 10.1053/eujp.2001.0284. PMID: 11798222.
Article
14. Oh TK, Jeon YT, Choi JW. 2019; Trends in chronic opioid use and association with five-year survival in South Korea: a population-based cohort study. Br J Anaesth. 123:655–63. DOI: 10.1016/j.bja.2019.08.012. PMID: 31558315.
Article
15. Lee JH. 2019; The opioid epidemic and crisis in US: how about Korea? Korean J Pain. 32:243–4. DOI: 10.3344/kjp.2019.32.4.243. PMID: 31569915. PMCID: PMC6813894.
Article
16. Consensus Statement from the American Academy of Pain Medicine and the American Pain Society. 2010; The use of opioids for the treatment of chronic pain. J Pharm Care Pain Symptom Control. 6:97–102. DOI: 10.1300/J088v06n01_08.
17. Kalso E, Edwards JE, Moore RA, McQuay HJ. 2004; Opioids in chronic non-cancer pain: systematic review of efficacy and safety. Pain. 112:372–80. DOI: 10.1016/j.pain.2004.09.019. PMID: 15561393.
Article
18. Noble M, Treadwell JR, Tregear SJ, Coates VH, Wiffen PJ, Akafomo C, et al. 2010; Long-term opioid management for chronic noncancer pain. Cochrane Database Syst Rev. 2010:CD006605. DOI: 10.1002/14651858.CD006605.pub2. PMID: 20091598. PMCID: PMC6494200.
Article
19. Furlan AD, Sandoval JA, Mailis-Gagnon A, Tunks E. 2006; Opioids for chronic noncancer pain: a meta-analysis of effectiveness and side effects. CMAJ. 174:1589–94. DOI: 10.1503/cmaj.051528. PMID: 16717269. PMCID: PMC1459894.
Article
20. Eisenberg E, McNicol ED, Carr DB. 2005; Efficacy and safety of opioid agonists in the treatment of neuropathic pain of nonmalignant origin: systematic review and meta-analysis of randomized controlled trials. JAMA. 293:3043–52. DOI: 10.1001/jama.293.24.3043. PMID: 15972567.
Article
21. Ballantyne JC. 2007; Opioid analgesia: perspectives on right use and utility. Pain Physician. 10:479–91. PMID: 17525783.
22. Portenoy RK, Farrar JT, Backonja MM, Cleeland CS, Yang K, Friedman M, et al. 2007; Long-term use of controlled-release oxycodone for noncancer pain: results of a 3-year registry study. Clin J Pain. 23:287–99. DOI: 10.1097/AJP.0b013e31802b582f. PMID: 17449988.
Article
23. Anderson VC, Burchiel KJ. 1999; A prospective study of long-term intrathecal morphine in the management of chronic nonmalignant pain. Neurosurgery. 44:289–300. DOI: 10.1097/00006123-199902000-00026. PMID: 9932882.
Article
24. Fishbain DA, Cole B, Lewis J, Rosomoff HL, Rosomoff RS. 2008; What percentage of chronic nonmalignant pain patients exposed to chronic opioid analgesic therapy develop abuse/addiction and/or aberrant drug-related behaviors? A structured evidence-based review. Pain Med. 9:444–59. DOI: 10.1111/j.1526-4637.2007.00370.x. PMID: 18489635.
Article
25. Juurlink DN, Dhalla IA. 2012; Dependence and addiction during chronic opioid therapy. J Med Toxicol. 8:393–9. DOI: 10.1007/s13181-012-0269-4. PMID: 23073725. PMCID: PMC3550262.
Article
26. Webster LR, Webster RM. 2005; Predicting aberrant behaviors in opioid-treated patients: preliminary validation of the Opioid Risk Tool. Pain Med. 6:432–42. DOI: 10.1111/j.1526-4637.2005.00072.x. PMID: 16336480.
Article
27. Kim ED, Lee JY, Son JS, Byeon GJ, Yeo JS, Kim DW, et al. 2017; Guidelines for prescribing opioids for chronic non-cancer pain in Korea. Korean J Pain. 30:18–33. DOI: 10.3344/kjp.2017.30.1.18. PMID: 28119768. PMCID: PMC5256264.
Article
28. Kahan M, Wilson L, Mailis-Gagnon A, Srivastava A. National Opioid Use Guideline Group. 2011; Canadian guideline for safe and effective use of opioids for chronic noncancer pain: clinical summary for family physicians. Part 2: special populations. Can Fam Physician. 57:1269–76. e419–28. PMID: 22084456. PMCID: PMC3215603.
29. Woo A, Lechner B, Fu T, Wong CS, Chiu N, Lam H, et al. 2015; Cut points for mild, moderate, and severe pain among cancer and non-cancer patients: a literature review. Ann Palliat Med. 4:176–83. DOI: 10.3978/j.issn.2224-5820.2015.09.04. PMID: 26541396.
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