Kosin Med J.  2020 Jun;35(1):58-63. 10.7180/kmj.2020.35.1.58.

Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma Arising from the Tongue: case report

• Kim YC
• Ryu S
• Won SJ
• Park JJ

• KMID: 2503730
• DOI: http://doi.org/10.7180/kmj.2020.35.1.58

Abstract

Liposarcomas are common mesenchymal malignant tumors arising from adipose tissue. Although liposarcomas are the most frequent type of soft tissue sarcomas, accounting for approximately 20% of all soft tissue sarcomas, they are rare in the head and neck, particularly in the oral cavity. Oral liposarcomas have been reported to occur mainly on the buccal mucosa, with other sites including the floor of the mouth, tongue, palate, and mandible. This report describes a 76-yearold male patient with an atypical lipomatous tumor/well-differentiated liposarcoma of the tongue that underwent surgical excision. This report also reviews published data on these rare tumors.

Keyword

Atypical lipomatous tumor; Tongue; Well-differentiated liposarcoma

Figure

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  Fig. 1 Laryngoscopic finding, showing a 1 × 1cm sized yellowish mass arising from the right anterior lateral tongue. The mass had smooth surfaces and was well encapsulated.

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  Fig. 2 Preoperative magnetic resonance imaging (MRI) of the tongue mass. (A) Transverse T1-weighted MRI showing a well-defined, ovoid-shaped mass with homogeneous high-signal intensity. (B) Transverse, fat-suppressed T1-weighted, gadolinium-enhanced MRI showing attenuated signal intensity inside the lesion.

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  Fig. 3 Pathologic finding. An atypical lipomatous tumor showing mature adipocytes with great variations in size and shape in fibrous stroma (H&E, ×100)

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  Fig. 4 Lesion removed during the second operation. The specimen was about 6 x 2.5 x 1 cm in size, including a 2 cm safety margin.

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