J Korean Med Sci.
2020 Jun;35(24):e231. 10.3346/jkms.2020.35.e231.
A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance
- Affiliations
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- 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
- 2Department of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea
- 3Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea
- KMID: 2503019
- DOI: http://doi.org/10.3346/jkms.2020.35.e231
Abstract
- There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.
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