Clin Endosc.  2020 May;53(3):377-378. 10.5946/ce.2020.134.

A Rare Cause of Gastric Subepithelial Tumor

Affiliations
  • 1Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea
  • 2St. Mary Pathology Laboratory, Busan, Korea


Figure

  • Fig. 1. (A) Initial endoscopy reveals a small subepithelial tumor at the gastric lower body. (B) On follow-up endoscopy 6 months later, the tumor has increased in size, but no erosion or ulceration is noted. (C) On endoscopic ultrasonography, the tumor is a 1.5 cm-sized, heterogeneously hypoechoic lesion in the deep mucosal and submucosal layers. (D) The resected specimen after endoscopic submucosal dissection.

  • Fig. 2. (A) Histopathological examination reveals spindle tumor cells under myxoid stroma with lymphoplasmacytic infiltration among the tumor cells (hematoxylin and eosin, ×400). (B) The spindle cells are immunopositive for smooth muscle actin and vimentin, and immunonegative for chromogranin, S-100, C-kit, DOG1, and anaplastic lymphoma kinase (smooth muscle actin, ×200).


Reference

1. Shi H, Wei L, Sun L, Guo A. Primary gastric inflammatory myofibroblastic tumor: a clinicopathologic and immunohistochemical study of 5 cases. Pathol Res Pract. 2010; 206:287–291.
Article
2. Cook JR, Dehner LP, Collins MH, et al. Anaplastic lymphoma kinase (ALK) expression in the inflammatory myofibroblastic tumor: a comparative immunohistochemical study. Am J Surg Pathol. 2001; 25:1364–1371.
3. Park SG, Kim GH, Park HJ, Kahng DH, Lee BE, Park DY. [Case of an inflammatory myofibroblastic tumor of the duodenum]. Korean J Gastroenterol. 2018; 72:28–32.
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