Obstet Gynecol Sci.  2020 Apr;63(3):286-292. 10.5468/ogs.2020.63.3.286.

Questionnaire survey on the management of pregnant women with preterm premature rupture of membranes

  • 1Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, Research Institute of Medical Science, Konkuk University, School of Medicine
  • 2Department of Obstetrics and Gynecology, Samsung medical Center, Sungkyunkwan University, School of Medicine
  • 3Department of Obstetrics and Gynecology, Konkuk University, School of Medicine
  • 4Department of Obstetrics and Gynecology, National Evidence-based Collaborating Agency; Department of Obstetrics and Gynecology
  • 5Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea, Seoul
  • 6Department of Obstetrics and Gynecology, Ajou University, School of Medicine, Suwon, Korea


The aim of this survey was to study the status of the actual practice in the management of preterm premature rupture of membranes (PPROM) between 34.0 and 36.6 weeks of gestation.
This survey was designed for obstetricians who work in secondary or tertiary medical institutions and attended the Korean Society of Maternal Fetal Medicine conference held on July 1, 2017, in Korea, using a structured questionnaire consisting of 5 questions.
The most commonly used antibiotic was cephalosporin monotherapy (34.5%). Antenatal corticosteroids were applied up to 34.0 weeks of gestation in half of the respondents. The frequency of expectant management was higher than that of immediate delivery in women with PPROM between 34.0 and 36.6 weeks of gestation (57.4%). The most important factor in determining immediate delivery was the symptoms of chorioamnionitis.
The present survey showed a considerable variation in the actual management of PPROM in women, especially the optimal timing of delivery. More evidenced-based studies with statistical power are required to decrease the heterogeneity of clinical practice.


Fetal membranes, premature rupture; Antibacterial agents; Betamethasone; Dexamethasone; Delivery, obstetric
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