Pediatr Infect Vaccine.  2020 Apr;27(1):62-68. 10.14776/piv.2020.27.e2.

Isolated Sphenoid Sinusitis withNontypeable Haemophilus influenzae Bacteremia in a Healthy Child

  • 1Department of Pediatrics, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, the Republic of Korea
  • 2Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University College of Medicine, Chuncheon, the Republic of Korea
  • 3Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, the Republic of Korea


Acute bacterial sinusitis is one of the most common diseases in children, and 5–13% of patients with viral upper respiratory infection experience secondary bacterial sinusitis as a complication. Isolated sphenoid sinusitis is rarer than frontal, maxillary, and ethmoid sinusitis. However, it presents potentially devastating complications, such as cranial nerve involvement, brain abscess, and meningitis, owing to its anatomical location. Nontypeable Haemophilus influenzae (NTHi) commonly causes acute bacterial sinusitis but rarely causes bacteremia, particularly in immunocompetent patients. We present a rare case of a 14-year-old boy with bacteremia due to isolated sphenoid sinusitis caused by NTHi.


Sphenoid sinusitis; Headache; Haemophilus influenzae; Bacteremia
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