Brain Tumor Res Treat.  2020 Apr;8(1):62-65. 10.14791/btrt.2020.8.e8.

An Intracerebral Type of Cranial Chondroma

Affiliations
  • 1Department of Neurosurgery, Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea

Abstract

The vast majority of intracranial chondromas are located in the base of the cranium. Their presentation as an intracerebral neoplasm is considered to be extremely rare. A previously healthy 45-year-old man experienced recurrent seizure attacks over a period of 6 months. Imaging studies of the brain revealed an ovoid and calcified mass which involve the cortex in the left frontal lobe. Intraoperatively, the mass had no adhesion to the dura and arachnoid membrane. The tumor was completely removed and the final diagnosis was intracerebral chondroma. The patient remained free of disease over the period of 18-years follow-up. This communication adds an unusual case to the literature on the chondroma that expressed in the form of an intra-axial space-occupying lesion in the frontal lobe.

Keyword

Brain neoplasm; Chondroma; Frontal lobe; Intracerebral

Figure

  • Fig. 1 MR images reveal an oval-shaped mass which involve the cortex in the left frontal lobe. A: T2-weighted image depicts an intracerebral mass with a hypointense periphery and relatively hyperintense central core. B–D: It is hypointense to gray matter and rim-enhanced on T1-weighted images. E: There is no evidence of tumor recurrence on the enhanced CT scan taken 18 years later after the surgery.

  • Fig. 2 Light microscopy of the tumor displays a gray-blue cartilage matrix and mature chondrocytes (hematoxylin and eosin staining, ×200).


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