Brain Tumor Res Treat.  2020 Apr;8(1):57-61. 10.14791/btrt.2020.8.e2.

Sinonasal Teratocarcinosarcoma, a Rare Tumor Involving Boththe Nasal Cavity and the Cranial Cavity

Affiliations
  • 1Departments of Neurosurgery, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea
  • 2Department of Neurosurgery, Kyungpook National University Chilgok Hospital, Kyungpook National University School of Medicine, Daegu, Korea
  • 3Departments of Pathology, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea

Abstract

Sinonasal teratocarcinosarcoma (SNTCS), a very rare tumor, is known to be a heterogeneous with epithelial, mesenchymal, and neuroepithelial components and shows a very aggressive clinical course. Due to the heterogeneity of this tumor, it is often misdiagnosed. No definitive treatment modality has been reported because it is a very rare tumor. A 44-year-old man presented to a rhinologist with headache and nasal obstruction, and an intranasal tumor was found that invaded into the cranial cavity. He underwent combined surgery with a rhinologist and a neurosurgeon following cognitive decline that worsened after a transnasal biopsy. The patient was diagnosed with SNTCS and underwent radiotherapy. However, residual tumor was found during radiotherapy and additional chemotherapy was administered. Follow-up brain MRI revealed no remnant or recurrent lesion. SNTCS is a tumor that has not yet been well researched and should be further investigated for proper treatment.

Keyword

Teratocarcinosarcoma; Brain tumor; Chemotherapy; Radiotherapy
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