J Korean Orthop Assoc.  1974 Jun;9(2):247-254. 10.4055/jkoa.1974.9.2.247.

Metastatic Bone Cancer (Clinical Observation on 63 Cases)

Affiliations
  • 1Department of Orthopedics, Medical School, Chonnam University, Kwangju, Korea.

Abstract

Among 1330 cancer patients consulted to and diagnosed in this University Medical School Hospital, from January of 1966 to August of 1972, 63 cases of them were confirmed to have cancers metastatic to bone. Clinical observation done on these 63 cases was as follows. 1. of 63 patients, 55 persons were all over their fourth decade of age and 27(42.8%) were at their fifth. Men were affected as twice as women. 2. Skeletal survey confirmed 94 sites of bone involvement in 63 cases and 77.5% of them were in either trunk or skull and mostly multiple. 3. Most frequent primary source in this series was lung (14 cases) and prostate cancer showed the highest metastatic rate of 57.1%. 4. Radiologically the osteolytic change was predominent in 82.5% of all metastatic foci. 5. First choice of treatment should be aimed for control of pain and walking aid rather than futile trial of radical procedure. Accordingly hormonal treatment, chemotherapy, local irradiation, and rigid fixation for pathological fracture should be applied.


MeSH Terms

Bone Neoplasms*
Drug Therapy
Female
Fractures, Spontaneous
Humans
Lung
Male
Prostatic Neoplasms
Schools, Medical
Skull
Walking

Figure

  • Fig. 1 Chest film of 58-year-old woman showed a large space-occupying lesion in the right mid-lung field, which was confirmed as a squamous cell ca by a needle biopsy.

  • Fig. 2 Fig. 1 patient was bed-ridden due to pathologic fracture of the right femur shaft.

  • Fig. 3 I-M nailing done for the fracture (Fig 2) enabled crutch walking immediately.

  • Fig. 4 63-year-old man with prostate ca had an extensive osteoblastic metastasis to entire pelvis and lower lumbar spines.

  • Fig. 5 52-year-old man. with highly undifferentiated adenocarcinoma of stomach sustained pathologic fracture on the right trochanteric region.

  • Fig. 6 Massive osteolytic changes at the right ilium and sacroiliac joint were due to metastasis of hypernephroma in 23-year-old school teacher.


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