J Korean Orthop Assoc.  1974 Sep;9(3):355-360. 10.4055/jkoa.1974.9.3.355.

Effect of 137Cs Whole Body Irradiation on the Peripheral Blood

• Moon MH

• KMID: 2471493
• DOI: http://doi.org/10.4055/jkoa.1974.9.3.355

Abstract

Radiobioloical effect of Cs whole body irradiation was assessed with observation on the peripheral blood pattern. Following irradiation of total amount of 800 R and 400 R respectively, in single and fractionated doses to the rabbits, peripheral blood pattern was studied for twenty days, with the results as follows. 1. Erythrocyte showed slight decrease from three to ten days following single irradiation, while the decrease was less pronounced in fractionated irradiation. Slight decrease of reticulocyte count was also shown in single irradiation group, while it was almost negligible in divided irradiation group. 2. Both single and divided irradiation were followed by marked decrease of leukocyte count from one to five post-irradiation days, followed by gradual return to normal thereafter. Percentile differential count showed that the decrease of lymphocyte count observed from one to three post-irradiation days was less marked in fractionated than in single irradiation group. 3. Mild decrease of thrombocyte count was showed from one to seven days following single irradiation and grom seven to ten days following divided irradiation. Hemoglobin value was below normal level from three to fifteen days after irradiation, though decreaseafter single irradiation was more marked than that after divided irradiation. 4. Effect of Cs whole body irradiationis, it can be inferred from this experimental result, almost proportional to the doses given and fractionated irradiation was less harmful than the single total irradiation in the same doses.

MeSH Terms

Blood Platelets
Erythrocytes
Leukocyte Count
Lymphocyte Count
Rabbits
Reticulocyte Count
Whole-Body Irradiation*