J Lipid Atheroscler.  2020 Jan;9(1):140-152. 10.12997/jla.2020.9.1.140.

The Effects of Meal Timing and Frequency, Caloric Restriction, and Fasting on Cardiovascular Health: an Overview

Affiliations
  • 1International Clinical Research Center, St. Anne's University Hospital, Brno, Czechia. manlio.vinciguerra@fnusa.cz
  • 2Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, University of Catania, Catania, Italy.
  • 3Division of Medicine, University College London (UCL), London, UK.

Abstract

Cardiovascular disease (CVD), which is the leading cause of death worldwide, is strongly affected by diet. Diet can affect CVD directly by modulating the composition of vascular plaques, and indirectly by affecting the rate of aging. This review summarizes research on the relationships of fasting, meal timing, and meal frequency with CVD incidence and progression. Relevant basic research studies, epidemiological studies, and clinical studies are highlighted. In particular, we discuss both intermittent and periodic fasting interventions with the potential to prevent and treat CVD.

Keyword

Fasting; Fasting mimicking diet; Caloric restriction; Blood pressure; Cardiovascular disease

MeSH Terms

Aging
Blood Pressure
Caloric Restriction*
Cardiovascular Diseases
Cause of Death
Diet
Epidemiologic Studies
Fasting*
Incidence
Meals*
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