Korean J Radiol.  2020 Mar;21(3):365-368. 10.3348/kjr.2020.0078.

Novel Coronavirus Pneumonia Outbreak in 2019: Computed Tomographic Findings in Two Cases

• Lin X
• Gong Z
• Xiao Z
• Xiong J
• Fan B
• Liu J

• KMID: 2470760
• DOI: http://doi.org/10.3348/kjr.2020.0078

Abstract

Since the 2019 novel coronavirus (2019-nCoV or officially named by the World Health Organization as COVID-19) outbreak in Wuhan, Hubei Province, China in 2019, there have been a few reports of its imaging findings. Here, we report two confirmed cases of 2019-nCoV pneumonia with chest computed tomography findings of multiple regions of patchy consolidation and ground-glass opacities in both lungs. These findings were characteristically located along the bronchial bundle or subpleural lungs.

Keyword

Severe acute respiratory infection; 2019 novel coronavirus; Computed tomography

MeSH Terms

China
Coronavirus*
Lung
Pneumonia*
Thorax
World Health Organization

Figure

• 

  Fig. 1 Thirty five-year-old man with 2019-novel coronavirus pneumonia. A–D. Axial computed tomography (CT) images of upper, middle, and lower lobes of right lung and lower lobe of left lung show multifocal regions of patchy consolidation and nodular ground-glass opacities, mainly distributed along bronchial bundles and subpleural regions. E. Coronal reformation CT image shows multifocal nodular groundglass opacities in right lower lung lobe.

• 

  Fig. 2 Thirty nine-year-old man with 2019-novel coronavirus pneumonia. A, B. High-resolution computed tomography images show ill-defined focal consolidation (arrow) along bronchovascular bundles in right lower lung lobe (A) and ill-defined ground-glass opacities (arrow) in subpleural regions of left lower lung lobe (B).

Reference

1. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020; 01. 24. [Epub]. DOI: 10.1056/NEJMoa2001017.

2. Chen Y, Liu Q, Guo D. Emerging coronaviruses: Genome structure, replication, and pathogenesis. J Med Virol. 2020; 01. 22. [Epub]. DOI: 10.1002/jmv.25681.

3. Lu H, Stratton CW, Tang YW. Outbreak of pneumonia of unknown etiology in Wuhan China: the mystery and the miracle. J Med Virol. 2020; 01. 16. [Epub]. DOI: 10.1002/jmv.25678.

4. Choi WJ, Lee KN, Kang EJ, Lee H. Middle East respiratory syndrome-coronavirus infection: a case report of serial computed tomographic findings in a young male patient. Korean J Radiol. 2016; 17:166–170.

5. Eurosurveillance Editorial Team. Note from the editors: novel coronavirus (2019-nCoV). Euro Surveill. 2020; 25:pii=2001231.

6. Corman VM, Landt O, Kaiser M, Molenkamp R, Meijer A, Chu DK, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill. 2020; 25:pii=2000045.

7. Gralinski LE, Menachery VD. Return of the coronavirus: 2019-nCoV. Viruses. 2020; 12:E135.

8. The Lancet. Emerging understandings of 2019-nCoV. Lancet. 2020; 395:311.

9. Rubin EJ, Baden LR, Morrissey S, Campion EW. Medical journals and the 2019-nCoV outbreak. N Engl J Med. 2020; 01. 27. [Epub]. DOI: 10.1056/NEJMe2001329.

10. Hui DS, I Azhar E, Madani TA, Ntoumi F, Kock R, Dar O, et al. The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China. Int J Infect Dis. 2020; 91:264–266.

11. Ooi GC, Khong PL, Müller NL, Yiu WC, Zhou LJ, Ho JC, et al. Severe acute respiratory syndrome: temporal lung changes at thin-section CT in 30 patients. Radiology. 2004; 230:836–844.

12. Müller NL, Ooi GC, Khong PL, Zhou LJ, Tsang KW, Nicolaou S. High-resolution CT findings of severe acute respiratory syndrome at presentation and after admission. AJR Am J Roentgenol. 2004; 182:39–44.