Korean J Neuromuscul Disord.  2019 Dec;11(2):55-58. 10.0000/kjnd.2019.11.2.55.

Severe Hyponatremia during Acyclovir Treatment in Shingles

Affiliations
  • 1Department of Neurology, Jeju National University School of Medicine, Jeju, Korea. oh.junghwan77@gmail.com
  • 2Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea.

Abstract

Acyclovir is effective in treating the herpes virus infection, especially chickenpox and shingles. Hyponatremia caused by acyclovir has been rarely reported. We present a shingles patient with symptomatic hyponatremia that was presumably caused by acyclovir affecting the hypothalamus or posterior pituitary gland. This case demonstrates that the serum electrolyte levels should be checked regularly and careful observation of symptoms such as nausea, convulsions, or mentality change is necessary in patients treated with acyclovir.

Keyword

Acyclovir; Hyponatremia; Herpes zoster; Inappropriate ADH syndrome

MeSH Terms

Acyclovir*
Chickenpox
Herpes Zoster*
Humans
Hyponatremia*
Hypothalamus
Inappropriate ADH Syndrome
Nausea
Pituitary Gland, Posterior
Seizures
Acyclovir
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