Mycobiology.  2019 Sep;47(3):340-345. 10.1080/12298093.2019.1628521.

Bisifusarium Delphinoides, an Emerging Opportunistic Pathogen in a Burn Patient with Diabetes Mellitus

Affiliations
  • 1Translational Research Division, Biomedical Institute of Mycological Resource, International St. Mary's Hospital and College of Medicine, Catholic Kwandong University, Incheon, Korea. sung97330@gmail.com
  • 2Department of Pathology, International St. Mary's Hospital, Catholic Kwandong University, Incheon, Korea.
  • 3Department of Laboratory Medicine, International St. Mary's Hospital, Catholic Kwandong University, Incheon, Korea. lmkjy7@gmail.com
  • 4Department of Microbiology, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do, Korea.

Abstract

An 82-year-old man with diabetes was admitted to the emergency department with a third-degree burn on his left leg. The deep swab specimen from his left leg was cultured on Sabouraud dextrose agar without cycloheximide and incubated at 25 °C for 5 days. On the basis of morphological characteristics and multigene phylogenetic analyses of the internal transcribed spacer region of ribosomal DNA and partial fragments of beta-tubulin and translation elongation factor 1-alpha, the causal agent of fungal skin infection was identified as Bisifusarium delphinoides, which was newly introduced by accommodating a Fusarium dimerum species complex. Thus, we describe here the first case of skin infection caused by B. delphinoides on a burn patient with diabetes mellitus based on morphological observation and molecular analysis.

Keyword

Antifungal susceptibility; FDSC; opportunistic pathogen; phylogenetic analysis

MeSH Terms

Agar
Aged, 80 and over
Burns*
Cycloheximide
Diabetes Mellitus*
DNA, Ribosomal
Emergency Service, Hospital
Fusarium
Glucose
Humans
Leg
Peptide Elongation Factors
Skin
Tubulin
Agar
Cycloheximide
DNA, Ribosomal
Glucose
Peptide Elongation Factors
Tubulin
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