Brain Neurorehabil.  2019 Mar;12(1):e1. 10.12786/bn.2019.12.e1.

Diffusion Metrics as a Potential Prognostic Biomarker in Cervical Myelopathy

Affiliations
  • 1Department of Physical Medicine and Rehabilitation, VHS Medical Center, Seoul, Korea.
  • 2Spine Center, Hallym University Sacred Heart Hospital, Anyang, Korea.
  • 3Department of Orthopedic Surgery, Hallym University Sacred Heart Hospital, Anyang, Korea.
  • 4Department of Physical Medicine and Rehabilitation, Hallym University Sacred Heart Hospital, Anyang, Korea. mdwooky@gmail.com

Abstract

Diffusion tensor imaging (DTI) has a diagnostic value in cervical myelopathy. The usefulness of diffusion metrics as a potential prognostic biomarker was assessed in this review. Various diffusion metrics, such as fractional anisotropy, mean diffusivity, apparent diffusion coefficient, and radial diffusivity, were significant in correlation with functional recovery after surgery. Changes in diffusion metrics not only at the compression level, but also above and below the compression level were confirmed. However, it was difficult to confirm the results owing to the diversity of studies. Further efforts to make a consensus on spinal cord DTI are needed.

Keyword

Diffusion Tensor Imaging; Cervical Myelopathy; Recovery of Function
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