Korean J Helicobacter Up Gastrointest Res.  2019 Sep;19(3):169-173. 10.7704/kjhugr.2019.19.3.169.

Association between Recurrence and Survival Rates According to the Location of Gastric Gastrointestinal Stromal Tumor

Affiliations
  • 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. ojh@catholic.ac.kr

Abstract

BACKGROUND/AIMS
This study aimed to evaluate the clinicopathological parameters of gastric gastrointestinal stromal tumors (GISTs) and to investigate the effect of tumor site on clinical outcomes.
MATERIALS AND METHODS
Patients treated for a surgically confirmed gastric GIST were retrospectively evaluated between January 2001 and June 2016. The risk level was determined on the basis of the tumor size and number of mitoses. The risk level, recurrence rate, and survival rates were evaluated on the basis of the site of the gastric GISTs.
RESULTS
The 97 patients identified included 42 men and 55 women. The median follow-up period was 36 months (range: 12~72 years). Of the 97 patients, 57 (58.7%) and 40 (41.3%) patients had proximally and distally located gastric GISTs, respectively. The high- and low-risk groups had higher proportions of proximally and distally located tumors, respectively (P=0.033). The recurrence rates of proximal and distal GISTs were 8.8%, and 2.5%, respectively (P=0.307). The overall survival rate was not associated with the site of the gastric GISTs (P=0.549).
CONCLUSIONS
No relevant associations were found among recurrence, overall survival, and gastric GIST location.

Keyword

Follow-up studies; Gastrointestinal stromal tumors; Retrospective studies; Stomach neoplasms; Survival rate
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