Perinatology.  2018 Jun;29(2):89-96. 10.14734/PN.2018.29.2.89.

Amniotic Fluid Embolism: Maternal Disseminated Intravascular Coagulation, Cardiovascular Collapse, and Acute Hypoxic Cases Shortly after Delivery

Affiliations
  • 1Department of Obstetrics and Gynecology, Inha University Hospital, Inha University College of Medicine, Incheon, Korea. csran@inha.ac.kr

Abstract

Amniotic fluid embolism (AFE) is a fatal disease in only pregnant woman during labor and delivery. The pathologic findings that have demonstrated fetal squamous cells in the pulmonary circulation are no more specific. Then, clinically characteristic signs and symptoms, such as cardiovascular collapse, acute hypoxia, disseminated intravascular coagulation, mental change and laboratory findings are the key points for diagnosis. Having a doubt on those sign and symptoms is the beginning of diagnosis and promptly multidisciplinary management is required. Korean National Registry for AFE must be established and we have to find out the diagnostic criteria, possible etiology, pathophysiology, management and treatment for AFE.

Keyword

Pregnancy; Amniotic fluid embolism; Shock; Disseminated intravascular coagulation; Hypoxia

MeSH Terms

Amniotic Fluid*
Anoxia
Diagnosis
Disseminated Intravascular Coagulation*
Embolism, Amniotic Fluid*
Epithelial Cells
Female
Humans
Pregnancy
Pregnant Women
Pulmonary Circulation
Shock
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