Obstet Gynecol Sci.  2020 Jan;63(1):98-101. 10.5468/ogs.2020.63.1.98.

Ovarian dysgerminoma with Müllerian anomaly: a case report

Affiliations
  • 1Department of Obstetrics and Gynecology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea. hellojungmi@hanmail.net
  • 2Paik Institute for Clinical Research, Inje University College of Medicine, Busan, Korea.
  • 3Department of Pathology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.

Abstract

Müllerian anomalies are rare deformities in women, and only a few cases concerning gynecologic malignancies arising in patients with congenital uterine malformations have been reported. Herein, we present the case of a 34-year-old woman with dysgerminoma with a Müllerian anomaly (uterus didelphys). She had secondary amenorrhea, and an ovarian mass and uterus didelphys were discovered during examination. After right salpingo-oophorectomy, the tumor was confirmed as dysgerminoma, and a chromosome study revealed a normal female karyotype (46, XX). The patient completely responded to 6 cycles of chemotherapy. To our knowledge, this is the first reported case of dysgerminoma with uterus didelphys. Although gynecologic malignancies in patients with Müllerian anomalies are very rare, clinicians should be aware of the coexistence of gynecologic malignancies and uterine malformations.

Keyword

Müllerian anomaly; Uterus didelphys; Gynecologic malignancy; Dysgerminoma
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