J Clin Neurol.  2020 Jan;16(1):166-168. 10.3988/jcn.2020.16.1.166.

Immune-Mediated Peripheral Neuropathy in Patients with Diffuse Panbronchiolitis

• Kang YR
• Nam TS
• Lee KH
• Kim S
• Park HJ
• Lee SJ
• Lee SH
• Kim BC

• KMID: 2467803
• DOI: http://doi.org/10.3988/jcn.2020.16.1.166

Abstract

No abstract available.

MeSH Terms

Humans
Peripheral Nervous System Diseases*

Figure

• 

  Fig. 1 Histopathological features of patient 1. A: Sural nerve biopsy shows a markedly inflamed blood vessel (arrow) between peripheral nerve bundles. B: The obliterated arteriole has fragmented elastic laminae (arrowhead) and dense lymphoplasmacytic infiltrates in the wall (A and B: hematoxylin and eosin stain, ×40 and ×100, respectively). C: Leukocyte common antigen immunohistochemistry highlights inflammatory cells in the vascular walls (×200). D: Epon section shows few remaining myelinated fibers with a myelin bulb (arrows) and blood vessels with inflammatory cells (arrowheads) (toluidine blue stain, ×200).

Reference

1. Poletti V, Casoni G, Chilosi M, Zompatori M. Diffuse panbronchiolitis. Eur Respir J. 2006; 28:862–871.

2. Park J, Banno S, Sugiura Y, Yoshikawa K, Naniwa T, Wakita K, et al. Microscopic polyangiitis associated with diffuse panbronchiolitis. Intern Med. 2004; 43:331–335.

3. Collins MP, Dyck PJ, Gronseth GS, Guillevin L, Hadden RD, Heuss D, et al. Peripheral Nerve Society Guideline on the classification, diagnosis, investigation, and immunosuppressive therapy of non-systemic vasculitic neuropathy: executive summary. J Peripher Nerv Syst. 2010; 15:176–184.

4. Flament T, Bigot A, Chaigne B, Henique H, Diot E, Marchand-Adam S. Pulmonary manifestations of Sjögren’s syndrome. Eur Respir Rev. 2016; 25:110–123.

5. Fardet L, Petersen I, Nazareth I. Common infections in patients prescribed systemic glucocorticoids in primary care: a population-based cohort study. PLoS Med. 2016; 13:e1002024.