Korean J Med.
2019 Dec;94(6):495-499. 10.3904/kjm.2019.94.6.495.
Sepsis
- Affiliations
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- 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. lungdrcho@snubh.org
- KMID: 2467215
- DOI: http://doi.org/10.3904/kjm.2019.94.6.495
Abstract
- Diagnosis and treatment criteria were recently updated based on the Sepsis-3 guidelines, which recommend the sequential organ failure assessment for accurate characterization of organ dysfunction. Large randomized controlled trials have found neutral results with early goal-directed therapy. To improve outcomes, treatment bundles incorporating standards for early sepsis treatment, including antibiotic and steroid treatment, were developed. Thus, future research should address the effects of steroids and immune-modulating agents on refractory septic shock as well as the development of new coagulopathy therapies and dynamic assessment tools.
