J Korean Orthop Assoc.  1971 Mar;6(1):27-35. 10.4055/jkoa.1971.6.1.27.

A Clinical Analysis of Bone and Joint Tuberculosis Complicated with Mixed Infection

Abstract

200 cases of bone and joint tuberculosis complicated with mixed infection treated at the Department of Orthopedic Surgery, National Medical Center through the year of 1958 to 1971 were analyzed and reported in this paper. 1. All the mixed infections complicated in bone and joint tuberculosis occurred secondarily as a complication of the formation of fistula in this series. 2. The incidence of the fistula formation as a complication of bone and joint tuberculosis was considerably higher as 117 out of 200 cases in the age group of 10-30 years compared with other age groups. Accordingly the incidence of mixed infection was higher in this age group than other groups in same proportion in this seiies. 3. Mixed infection occurred relatively earlier after the fistuIar was formed. 46 out of 200cases (23%) had mixed infection one month after the fistula was formed. 4. Majority of the fistula developed spontaneously as 129 out of 200 cases (64.5%) 5. 135 cases of fistula developed during the treatment with PAS. and INH, and 11 cases developed fistula during triple antituberculosis therapy with PAS. INH. and Streptomycin. 6. Majority of the causative microorganism was Staphylococcus aureus as 210 out 360 cultures. (58.3%). 7. The result of the treatment was evaluated, and the result of radical operation gave remarkably higher incidence of healing, 110 out of 130 cases, than that of medical treatment, 33 healing out of 64 cases.


MeSH Terms

Coinfection*
Fistula
Humans
Incidence
Joints*
Orthopedics
Staphylococcus aureus
Streptomycin
Tuberculosis, Osteoarticular*
Streptomycin
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