J Korean Ophthalmol Soc.  2019 Nov;60(11):1112-1116. 10.3341/jkos.2019.60.11.1112.

Infectious Crystalline Keratopathy Caused by Alternaria

Affiliations
  • 1Department of Ophthalmology, Daegu Fatima Hospital, Daegu, Korea. dj_oph_2540@hanmail.net

Abstract

PURPOSE
To report a case of infectious crystalline keratopathy caused by Alternaria in the corneal center. CASE SUMMARY: A 66-year-old male visited our clinic with right ocular pain and visual loss after corneal trauma caused by a foreign body hitting his right eye while performing farm work 1 month prior to his visit. The patient had no history of corneal surgery and long-term use of topical corticosteroid. A corneal epithelial defect and whitish snowflake margin infiltration around the corneal stroma were observed in the corneal center, but there was an absence of conjunctival injection and anterior segment inflammation. Cultures and a biopsy of the corneal scrapings revealed Alternaria species fungus. The patient was treated with 1% topical voriconazole and 0.5% moxifloxacin, together with oral voriconazole (400 mg/day). After 2 months of treatment, the disease was completely cured, with a minute corneal opacity.
CONCLUSIONS
We successfully treated a rare case of infectious crystalline keratopathy caused by Alternaria, which has not been previously reported in the Republic of Korea.

Keyword

Alternaria spp.; Corneal trauma; Infectious crystalline keratopathy
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