J Korean Radiol Soc.  1984 Mar;20(1):211-217. 10.3348/jkrs.1984.20.1.211.

A prospective study on the adverse reactions of intravascular administration of contrast media


In this prospective study, it was aimed to survey the icidence of untoward reactions and overall problemsoccurred when iodinated contrast media was used for the purpose of diagnostic radiology. So, the causes of adversereactions to the contrast media in 34 patients were analyzed from 474 cases, and the following results wereobtained; 1. The incedence of adverse reactions were noticed in 34 cases among 474 cases. (7.15%). 2. Positiveallergic history or previous examinations was not related to present examination statistically. 3. The erythema,less than 2mm in diameter after skin test was not paralleled with the occurreence of side reaction, but when over5mm, it was significantly associated with the reaction. 4. The incidence was neither related to sex or age, butthe requency was especially lower in person, below 20 years of age. 5. The frequent symptoms and signs in sidereactions were chilling (24.5%), nausea(22.6%), and flushing (15.1%0. 6. The dosage of Hypaque or dorray hadcorrelation with the incidence of side reactions, but Urografin and Billagrafin did not. 7. Patients experiencingfear and anxiety did not show any relationship in the incidence of adverse reactions.

MeSH Terms

Contrast Media*
Diatrizoate Meglumine
Prospective Studies*
Skin Tests
Contrast Media
Diatrizoate Meglumine
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