J Korean Orthop Assoc.  1979 Mar;14(1):171-175. 10.4055/jkoa.1979.14.1.171.

A Study on the Acrylamide Gel Electrophoretic Analysis of Joint Fluid Proteins

• Suh YH

• KMID: 2460659
• DOI: http://doi.org/10.4055/jkoa.1979.14.1.171

Abstract

Analysis of synovial fluid is a most helpful aid in diagnosis and differentiating the varlous types of arthritis. But little information is available on joint fluid proteins and immunoglobullns. The present study was designed to obtain more precise information about each component of joint fluid proteins, using Acrylamide Gel Microzone system with a Densitometer. The following results were obtained: 1. The amount of total protein in both types of arthritis was approximately twice as high as that in the normal group (Normal;2.12± 0.50g%, R.A.;4.51± 1.18g%, Tbc;4.10± 1.02g%). 2. The albumin fraction was decreased in both types of arthrltis (R.A.;42.15± 5.21g%, Tbc; 44.24± 5.61g%) in comparison with 65.25± 4.40g% in the normal group. 3. The percentages of Alpha 1 and Beta globulin in both types of arthritis were similar to that in the normal group. (Normal:Alpha 1;6.01± 1.10, beta; 12.40± 1.90) 4. The percentages of Alpha 2 globulin and gamma globulin in both types of arthritis were approximately twice as high as that in the normal group. (Normal:Alpha 2;5.31± 1.62, Gamrna; 11.03± 1.51).

MeSH Terms

Acrylamide*
Arthritis
Beta-Globulins
Diagnosis
gamma-Globulins
Joints*
Synovial Fluid
Acrylamide
Beta-Globulins
gamma-Globulins