Clinical Observation of Geut

Ha, Kwon Ick; Chang, Jin Kwan; Hyun, Chung; Kim, Jai Ho

Abstract

Gout is a hereditary condition of disturbed uric acid metabolism in which urate salts are deposited in articular, periarticular and subcutaneous tissues. Clinically, it is characterized by recurring attacks of acute arthritis, intervals of freedom from pain, and in late stages by crippling deforming arthritis, nephritis, urinary calculi and cardiovascular lesions. Seventeen patients with gout managed at the department of orthopedic surgery, National Police Hospital, from February, 1972 to December, 1977, were reviewed and the following results were obtained. 1. Most of cases were between 30 and 49 years old and all the cases were male. 2. The most common season of occurrence of acute attack was winter and the least common season was summer. 3. The recurring attacks were more frequent than the first attacks. 4. The precipitating factors could be found usually including family history, dietary indiscretions, exposure to cold and stress conditions. 5. The average serum uric acid level during acute attacks showed 12. 9mg% and all the cases except 2 cases noted increased ESR with average 33.9mm/hr. The leucocytosis were noted in 6 cases. 6. The first involved joints were the M-P joint of big toe in 13 cases and the knee joint in 3 cases. 7. The radiological multiple punched-out bone lesions were found in 8 cases. 8. One tablet (0. 65mg) of colchicine was given every hour until the diarrhea appeared or the pain subsided, in 13 cases. Among them, when 10 tablets of colchicine were taken, the diarrhea appeared in 10 cases and the pain subsided in 8 cases. So we recommend 7~8 tablets for relief of G-I discomfort in management of gout. 9. The cases of gouty arthritis may be found more and more in our country because the stress condition and meat intake might be increased such as in Europe and America.

Clinical Observation of Geut

Abstract

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