Nat Prod Sci.  2019 Sep;25(3):181-199. 10.20307/nps.2019.25.3.181.

Ethnobotany, Phytochemistry, and Pharmacology of Angelica decursiva Fr. et Sav.

Affiliations
  • 1Department of Chemistry and Biochemistry, Faculty of Arts and Science, Concordia University, 7141 Sherbrooke St. W., Montreal, Quebec, Canada.
  • 2Department of Biology, Faculty of Arts and Science, Concordia University, 7141 Sherbrooke St. W., Montreal, Quebec, Canada.
  • 3Centre for Structural and Functional Genomic, Dept. of Biology, Faculty of Arts and Science, Concordia University, 7141 Sherbrooke St. W., Montreal, QC, Canada.
  • 4Department of Food and Life Science, Pukyong National University, Busan 48513, Republic of Korea. choijs@pknu.ac.kr
  • 5Department of Food Science and Human Nutrition, Chonbuk National University, Jeonju 54896, Republic of Korea.

Abstract

Angelica decursiva Fr. et Sav. (Umbelliferae) has traditionally been used to treat different diseases due to its antitussive, analgesic, and antipyretic activities. It is also a remedy for thick phlegm, asthma, and upper respiratory infections. Recently, the leaf of A. decursiva has been consumed as salad without showing any toxicity. This plant is a rich in different types of coumarin derivatives, including dihydroxanthyletin, psoralen, dihydropsoralen, hydroxycoumarin, and dihydropyran. Its crude extracts and pure constituents possess anti-inflammatory, anti-diabetic, anti-Alzheimer disease, anti-hypertension, anti-cancer, antioxidant, anthelmintic, preventing cerebral stroke, and neuroprotective activities. This valuable herb needs to be further studied and developed not only to treat these human diseases, but also to improve human health. This review provides an overview of current knowledge of A. decursiva metabolites and their biological activities to prioritize future studies.

Keyword

Angelica decursiva; Umbelliferae; Coumarins; Bioactivity studies; Anti-inflammatory activity
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